To keep up with skyrocketing global demand for social networks and information, including everything from mobile data to high-definition video, content providers must scale and automate their operations as much as possible to keep costs low and performance high. Combining the speed and performance of optical networks with the automation and virtualization of SDN and NFV, and advanced Multi-Domain Service Orchestration (MDSO), can bring powerful benefits to content providers. This paper highlights primary advances in DCI and Data Center Federation that are helping to meet booming content demand, both inside and across data centers.